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Print Edition StoriesMonday, February 8, 2010
Yale researchers ID disease-treating proteins
By Mass High Tech staff
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Yale scientists have developed color-coded proteins that researchers can use to identify proteins to treat diseases, according to the school.
Anthony van den Pol, a professor of neurosurgery, and John Davis, a molecular biologist, have figured out how to use a mutation-prone virus engineered to express fluorescent proteins to find proteins researchers could use against diseases. The virus generates mutated genes that code for these proteins and expresses them within cells so scientists can study their function. The procedure could streamline research to identify and study novel mutant proteins, according to the researchers.
The researchers made the discovery while studying viruses as a means of attacking brain cancers.
The discovery is detailed in the February issue of the Journal of Virology.
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