Archive for the ‘Life Sciences’ Category

Save the mitochondria = cure Lou Gehrig’s disease

Wednesday, November 18th, 2009

Amyotrophic lateral sclerosis, better known as Lou Gehrig’s disease, is marked by the degeneration of motor neurons in the brain and spine. Beyond the sure signs of the disease that took the former New York Yankees player now also known as the namesake of ALS, however, little is known about its cause.

Now, a report in MIT Tech Review points to the possibility of treatment on the horizon. A drug made by French biotech Trophos aims to keep neurons in survival mode and away from degeneration mode.

Currently in clinical trials, the drug compound focuses specifically on nerve cell mitochondria and preventing any unhealthiness, dying off, or degeneration associated with it.

Read more…

MHT’s Women to Watch make an impression: Now to recognize more

Tuesday, November 17th, 2009

By Jim Connolly

Jim ConnollyThere are those people who walk into a room and enter into a discussion and you know right away, there’s something special about them. They are bright, well-informed, focused and energetic. They’re leaders. Put 10 of them in the room, and you have something dynamic.

That’s the way it was with the 2009 MHT Women to Watch event last spring.

Women to WatchYou had a room full of people like Cambridge Nanocomp’s Jill Becker who has been building and then selling “atomic layer deposition” systems, sort of like an oven used to develop nanoscale thin films, such as coatings for drillbits. But she often did it one-handed, with a baby in the other arm.

Intel’s Mondira Pant has a batch of microprocessor-related patent applications in the pipeline and has authored some 30 technical papers. She also has focused on developing her skills as a public speaker, being honored as the best speaker at an Intel technical conference, while reaching out to the community to teach dance.

Then, there was Anna Mracek Dietrich, one of the MIT rocket team alums that are building a roadable aircraft, what the rest of us might call a flying car. But Dietrich isn’t just a techie, she’s the business person behind the business at Terafugia. In addition, to show the wisdom of youth, as one of the youngest Women to Watch, she observed that she awaits the day when there will be no need for an event that focuses just on the achievements of women.

For now, though, it’s important to continue to recognize the accomplishments of the women who are driving forward the New England technology sector. So, for the seventh year, Mass High Tech will recognize the women who have contributed to the tech community, but also are poised to be industry leaders of the future.

Time is running out. We need you and your peers to nominate great candidates for the 2010 Women to Watch awards. As members of the tech community you know best who they are.

Nominations close on December 4, with honorees being celebrated on March 18. Please submit your nominations here.

Only two local projects in Time’s 50 Best Inventions of 2009

Friday, November 13th, 2009

Getting a jump on the year end-lists for 2009, Time has declared its Best Inventions of the Year. Some are impressive, some are scary, and many are things whose inclusion requires an inventive stretch of the definition of the word “invention.”

Before we get to that, only two of the inventions listed have local connections — an electric eye developed at MIT, and an electric microbe developed at UMass Amherst. Does Time know how many things get invented around here? I don’t either, but it’s a lot. I’m not sure how many would make the top 50 for a given year, but I’d imagine more than two. Have these people not seen the Happiness Hat? I was at MIT earlier this year and a robot made me ice cream in 30 seconds. That doesn’t rate?

Meanwhile, among the winners were: a paper airplane, a high-school football offense, and a method to Tweet by thought. All impressive, and they round out a 50-click editorial feature nicely, but cooler than SixthSense? One is a decision not to do something, one is a paper airplane, and one is the worst thing I’ve ever heard.

On the downside, the gas mask bra that won at the Ig Nobel awards a few months back was chosen as one of the five worst inventions of the year.

Rehab robots at Northeastern

Friday, November 13th, 2009

Tech Review takes a look at a robotic rehabilitation device developed by Northeastern’s Biomedical Mechatronics Laboratory. The NASA-inspired device — video here — is intended to help stroke victims regain muscle movement.

MIT spinout Myomo has developed similar technology, but ran into financial problems earlier this year. Earlier this year, MHT reported on similar technology being developed at MIT for people with cerebral palsy.

MIT spinout Cogito’s software analyzes voice to find depression

Thursday, November 5th, 2009

Technology Review takes a look at Charlestown-based Cogito Health, who has developed software to determine whether people are depressed or not based on an analysis of their voices.

The MIT Media Lab spinout is based on the research of Sandy Pentland.

Madoff-linked philanthropist Picower dead

Monday, October 26th, 2009

Jeffry Picower, the philanthropist behind the foundation that fundedPicower Institute for Learning and Memory at MIT, has died of a heart attack.

Picower’s name came up as an investor with Ponzi schemer Bernard Madoff, but he may have made more money than Madoff himself from the scheme. He’d been sued by the lawyer who is liquidating Madoff’s assets, who says Picower himself may have made more than $5 billion in fake profits.

In 2002, the Picower Foundation gave MIT $50 million to establish the Picower Center, which focuses on brain and cognitive research. After Madoff’s arrest in December 2009, the foundation shut down, saying it had run out of money.

Having trouble finding H1N1? Harvard Medical School releases Swine Flu tracking app

Monday, October 26th, 2009

Harvard Medical School has developed a H1N1-tracking iPhone app. The app is a project of HMS Mobile, which sounds like a British Navy ship, but says it’s a Harvard Medical group dedicated to helping people deal with day-to-day health emergencies.

Also — that’ll be two bucks. Just around the corner, those anti-capitalist hippies at Children’s Hospital, working with the MIT Media Lab, released their own, free H1N1 tracking app last month.

That’s two H1N1 apps sprouting from about one city block — If things keep up like this, pretty soon you should be able to use your mobile phone to track H1N1 germs chasing you down the street in real-time, or see the normally invisible H1N1 crawling over people’s faces in an augmented reality app, exposing them as the feverish, congested zombies they are.

Four locals among PopSci’s ‘Ten Young Geniuses’

Tuesday, October 20th, 2009

Popular Science has chosen “10 Young Geniuses Shaking Up Science Today,” and not surprisingly, four of them come from New England. Take that, Rest of the Country.

Among the 10:

PopSci also helpfully notes that, John Cusack notwithstanding, the planet Nibiru will not collide with Earth, wiping out all life, in two years.

Harvard researchers make beating “fruit roll-up” heart muscle out of stem cells

Thursday, October 15th, 2009

Good news for lab animals who have had heart attacks: Harvard researchers have grown a strip of beating mouse heart muscle from embryonic stem cells, according to the Globe’s White Coat Notes blog. The breakthrough will be detailed tomorrow in the journal Science.

Sure, it’s no human ear growing out of a mouse’s back, but it gets stem cell research that much closer to making replaceable parts for humans, or making a heart like a carburator.

Not to be outdone by the unnerving motion of a robot made from “jammable slurry,” one of the researchers compares the heart-muscle strip to a “fruit roll-up.” Delicious.

Invo Bioscience births a wailing med device success

Friday, October 9th, 2009

By Julie Donnelly

Julie DonnellyInvo Bioscience has a very special announcement to make — it is the proud parent of a fertility device that has produced its first baby.

The Beverly-based medical device firm’s Invocell device was launched in the Middle East early this year, and a healthy baby arrived on September 29 to a Pakistani mother. The mother, who is 40, was trying to get pregnant for 16 years.

The procedure involves combining sperm and eggs in a device that is implanted in the woman for three days to incubate. Then one or two resulting embryos are transferred to the uterus so it can implant and the pregnancy can continue.

The announcement is sweet because in the life sciences, tangible results are few and far between. Creating a drug, for instance, takes at least ten years and up to $1 billion. For medical devices, the FDA approval process is somewhat quicker and easier. But researchers and company executives alike still must possess tremendous patience and stamina getting life science products to market. There are many more failures than successes. And success is often measured in little increments, such as extending the life of a cancer patient for a few weeks.

But you can’t be a little pregnant. A woman in Pakistan can now happily attest to that.

Kudos, Invo Bioscience.

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